MEMS flow sensor for organ on a chip applications

Organ-on-a-chip systems are transforming biomedical research by enabling realistic in-vitro models of human organs. However, precise control and monitoring of fluid flow at the microscale remain a major challenge. This project explores a novel and revolutionary concept: mechanically coupled MEMS resonators as ultra-sensitive flow sensors, integrated directly into microfluidic channels. Unlike conventional flow sensors, this approach leverages the dynamic interaction between resonators to enhance sensitivity and resolution, potentially surpassing existing technologies in organ-on-a-chip applications.

The student will:

• Conduct a literature review on MEMS resonators, microfluidic sensing, and their application in biomedical research.
• Design a new class of mechanically coupled MEMS resonators optimized for flow sensing.
• Simulate their mechanical and fluidic behaviour to evaluate and optimize performance.

This project offers a unique opportunity to work at the intersection of MEMS and microfluidics, with potential impact in biomedical engineering by contributing to next-generation organ-on-a-chip platforms.

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Last modified: 2025-02-07